Onaven
I have noticed a few times when interacting with things such as a door, or a fight, I get stuck with the spinning cursor. This has happened twice now. Chat still works, but I am unable to interact with anything and I can only ALT F4 out of the game. The last time this happened I had to get a mod to unghost me as it still had me logged in.
Specifically this has only happened in Avalon, once trying to enter the Avalon Institute (weapon skill side) and doing a 3 devil 3 snake fight in the Underground.